| William Atherton | ... Dr. Destiny / John Dee |
| Rene Auberjonois | ... Kanjar Ro |
| Morena Baccarin | ... Black Canary / Dinah Lance |
| Powers Booth | ... Gorilla Grodd |
| Julie Bowen | ... Aresia / Helena Kosmatos |
| Clancy Brown | ... Lex Luthor |
| Ian Buchanan | ... Ultra-Humanite |
| Corey Burton | ... Brainiac, Steppenwolf |
| Jeffery Combs | ... The Question |
| Olivia d'Abo | ... Star Sapphire |
| Keith David | ... Despero |
| Michael Dorn | ... Kalibak |
| Larry Drake | ... Colonel Vox |
| Robert Englund | ... Felix Faust |
| Oded Fehr | ... Dr. Fate / Kent Nelson |
| Robert Foxworth | ... Professor Emil Hamilton |
| Peri Gilpin | ... Volcana / Claire Selton |
| Richard Green | ... Orm |
| Jennifer Hale | ... Zatanna Zatara |
| Mark Hamill | ... The Joker |
| Jason Hervey | ... Dove / Donald Hall |
| Michael Ironside | ... Darkseid |
| Juliet Landau | ... Tala |
| Jason Marsden | ... Snapper Carr |
| Karen Maruyama | ... Tsukuri |
| Stephen McHattie | ... The Shade |
| Phil Morris | ... Vandal Savage |
| Ron Perlman | ... Clayface / Matt Hagen |
| C.C.H. Pounder | ... Amanda Waller |
| Sheryl Lee Ralph | ... Cheetah / Barbara Ann Minerva |
| James Remar | ... The Manhunters |
| John Rhys-Davies | ... Hades |
| Eric Roberts | ... Mongul |
| Mark Rolston | ... Firefly / Garfield Lynns |
| Scott Rummel | ... Aquaman / King Arthur of Atlantis |
| Fred Savage | ... Hawk / Hank Hall |
| Armin Shimmerman | ... Dr. Achilles Milo |
| Kin Shriner | ... Green Arrow / Oliver Queen |
| J.K. Simmons | ... General Wade Eiling |
| Tom Sizemore | ... Metamorpho / Rex Mason |
| Lane Smith | ... Simon Stagg |
| William Smith | ... Draaga |
| Michael T. Weiss | ... Etrigan / Jason Blood |
| Michael Jai White | ... Doomsday |
| José Yenque | ... Copperhead |
| Rachel York | ... Circe |
| Rob Zombie | ... Ichthultu |
