It is some years after the first Rescuers movie, and Bernard and Bianca have gone on many successful missions for the Rescue Aid Society. Their next adventure however may be one of their toughest yet as the pair journey to Australian to rescue a boy, Cody, who is struggling to save a magnificent golden eagle. Cody's been kidnapped by the notorious poucher, McLeach, who wants the boy to reveal the eagle's location to him. It's an all out race for the mice and their "down under" guide, Jake, to get to the boy and the eagle before they both become extinct.