A cross between cyberpunk and film noir, Spicy City, according to Gary Susman of Boston Phoenix, is 'a near-future world where technology has divorced mind from body, via virtual reality, organ transplants, cloning, and genetic engineering. Human bodies are cumbersome, defective machines, and the healthy are vulnerable as sources of spare parts -- often harvested by force, manufactured through cloning, and sold on the black market. New, drug-resistant viruses are a constant threat. As these themes accrue over the course of the series, they imply a rich, overarching vision of a biomechanical nightmare future.'

Each episode is narrated by a nightclub owner called Raven.