After his murder, CIA operative Al Simmons makes a deal with the devil Malebolgia. Five years later, Al is brought is brought back to life as Spawn, a powerful agent of Hell. As he struggles to remember his past life, he finds himself drawn to his former wife Wanda and becomes entangled with the local Mafia. Taking refuge in an alley, Spawn battles the forces of evil outside – encouraged by a mysterious, twisted Clown – as well as the evil within himself. Given an ominous warning by the sage Cogliostro, Spawn must learn the rules of the game and choose a side; before the final war between Heaven and Hell begins.